Divided into eight thematic sections, the Handbook explores key methodological approaches, concepts, and issues, as well as current controversies within various denominations. Selected essays draw on reason as a distinct source of theology, discussing evolutionary biology and behavioural genetics, psychology, anthropological research, philosophical research, and queer theory. It examines the history of in theologies of sexuality and gender, with close analysis of the Bible and the Christian tradition. The final section considers theology in relation to different expressions of sexual identities. This volume is an essential reference for students and scholars, which will also stimulate further research.