The primary reason for Fortuna's longevity is that she was a conceptual deity, symbiotically connected to the concept of chance and good fortune. When communities, individuals, and social groups interacted with the goddess, they were inevitably also interacting with the concept: renegotiating it, enriching it with new meanings, and challenging established associations. All the available literary, epigraphic, and archaeological sources on Fortuna are explored here in depth, including analyses of all the attested sanctuaries of the goddess in Italy, an updated study of inscribed gifts offered to her by a variety of individuals, and discussion of how authors such as Cicero and Caesar wrote about Fortuna, chance, and good luck. This study of the goddess based on conceptual analysis serves to construct a radically new picture of the historical development of this deity in the context of the cultural interactions taking place in ancient Italy, and also suggests a new approach to polytheism based on an exploration of the connection between gods and goddesses and concepts.