This book delivers a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks--a fundamental aspect of computational systems biology. The book covers key modelling paradigms in detail, while at the same time retaining a simplicity that will appeal to those from less quantitative fields.

Key Features:

• A hands-on approach to modelling
• Covers a broad spectrum of modelling, from static networks to dynamic models and constraint-based models
• Thoughtful exercises to test and enable understanding of concepts
• State-of-the-art chapters on exciting new developments, like community modelling and biological circuit design
• Emphasis on coding and software tools for systems biology
• Companion website featuring lecture videos, figure slides, codes, supplementary exercises, further reading, and appendices: https: //ramanlab.github.io/SysBioBook/

An Introduction to Computational Systems Biology: Systems-Level Modelling of Cellular Networks is highly multi-disciplinary and will appeal to biologists, engineers, computer scientists, mathematicians and others.