Male Sterility and Motility Disorders: Etiological Factors and Treatment

I. The Immotile Sperm: Etiology.- 1. Motility Update.- 2. Metabolic Strategy in Human Spermatozoa: Its Impact on Sperm Motility.- 3. Extrinsic Factors Affecting Sperm Motility: Immunological and Infectious Factors and Reactive Oxygen Species.- 4. Intracellular Calcium and Sperm Motility.- 5. Genetic Aspects of Sperm Motility Disorders.- 6. Necrospermia: Etiology and Management.- II. Therapeutic Possibilities for Motility Disorders.- 7. In Vivo Therapies for Asthenozoospermia.- 8. In Vitro Therapy for Sperm Motility: Specific and Nonspecific Treatments.- III. ICSI Option for Immotile Sperm.- 9. Injection Procedures of Immotile Sperm: Selection, Tail Breakage, and Viscous Solutions.- 10. Fertilizing Capability of Frozen-Thawed Immotile Sperm.- 11. Clinical Aspects of ICSI with Immotile Sperm.- 12. Intracytoplasmic Sperm Injection in Difficult Cases: The Egyptian Experience.- 13. Difficult Cases in ICSI (Male Factors).- 14. ICSI in Difficult Cases: Total Absence of Both Motile and Normal Spermatozoa.- 15. Difficult ICSI Cases: An Israeli Survey.- IV. Testicular Sperm: Physiological to Pathological Aspects.- 16. Growth Factors in Testis Development and Function.- 17. Microinsemination Using Spermatogenic Cells in Mammals.- 18. Cell Loss During Spermatogenesis: Apoptosis or Necrosis?.- 19. Regulation of Apoptosis in the Testis.- V. Testicular Sperm Retrieval.- 20. Thermic and Metabolic Microsensors for Testicular Sperm Extraction (TESE) Before ICSI.- 21. ICSI with Epididymal and Testicular Sperm Retrieval.- 22. Pathophysiologic Changes after Testicular Sperm Extraction: Patterns and Avoidance of Testicular Injury.- 23. Cytological Evaluation of Germinal Populations as Part of a Testicular Sperm Retrieval Strategy.- VI. Conceptus Quality in ICSI with Testicular Sperm and Ethical Problems of ART.- 24. Genetic Aspects of Male Sterility.- 25. Conceptus Quality from ICSI with Testicular Sperm.- 26. Genetic Problems and Congenital Malformations in 1987 ICSI Children.- 27. Ethical Dilemmas in Assisted Reproduction.- Author Index.