From Madness to Mental Health neither glorifies nor denigrates the contributions of psychiatry, clinical psychology, and psychotherapy, but rather considers how mental disorders have historically challenged the ways in which human beings have understood and valued their bodies, minds, and souls.

Greg Eghigian has compiled a unique anthology of readings, from ancient times to the present, that includes Hippocrates; Julian of Norwich's Revelations of Divine Love, penned in the 1390s; Dorothea Dix; Aaron T. Beck; Carl Rogers; and others, culled from religious texts, clinical case studies, memoirs, academic lectures, hospital and government records, legal and medical treatises, and art collections. Incorporating historical experiences of medical practitioners and those deemed mentally ill, From Madness to Mental Health also includes an updated bibliography of first-person narratives on mental illness compiled by Gail A. Hornstein.