Molecular Driving Forces, Second Edition is an introductory statistical thermodynamics text that describes the principles and forces that drive chemical and biological processes. The second edition includes an additional chapter on thermodynamics and two new chapters: (1)"Microscopic Dynamics" which explores single molecule experiments; and (2) "Bio and Nano Machines" which describes the workings of biological molecules including proteins and DNA. New examples and practical applications are integrated throughout the revised and updated text, exploring topics in biology, environmental and energy science, and nanotechnology. It also includes new end-of-chapter problems, and purely mathematical topics are now in appendices. Written in a clear and reader-friendly style, the book provides an excellent introduction to the subject for novices while remaining a valuable resource for experts.