Oral health is essential for maintaining systematic health. A good oral health can decrease the risk of various systemic diseases, such as rheumatoid arthritis, cardiovascular disease and diabetes. Oral diseases are linked to other diseases of the body due to the natural reaction of the human body towards harmful stimuli, which is known as inflammatory response. It is the body's warning response towards viruses and infections. The common symptoms of inflammation include pain, swelling, redness, heat and limited function. Rheumatoid arthritis, cardiovascular disease, gum diseases and diabetes all have similar type of inflammatory response. Severe gum disease can increase systemic inflammation, which develops in the background and may turn into severe systemic diseases. Oral bacteria trigger the formation of C-reactive proteins (CRPs), which cause inflammation resulting in the formation of clots in the arteries, thereby increasing the risk of stroke and heart diseases. The topics included in this book on oral health and systemic diseases are of utmost significance and bound to provide incredible insights to readers. It will serve as a valuable source of reference for graduate and post graduate students.