This updated third edition addresses the difficulties that the autistic syndrome presents for the clinician, with diagnostic aids and clear guidelines for medical evaluation. These two world authorities provide detailed explanations of current knowledge of the molecular biology and genetics of the syndrome. New chapters discuss adults with autism, behavior complexes, and neurology. Other features are reviews of available medical therapies and updates on other interventions, such as psychoeducation and behavioral modification procedures. The authors encompass all aspects of the syndrome and its management and conclude with an essential integration of current knowledge from diverse fields.