Pathogenesis and Treatments of Head and Neck Cancer

This Special Issue reprint compiles cutting-edge research on the pathogenesis and treatment of head and neck squamous cell carcinoma (HNSCC). The collected articles explore metabolic reprogramming and immune evasion mechanisms, highlighting the roles of enzymes such as IDO1 and IL4I1. Studies on gene expression profiles, including SLC2A3 and SDHA, provide insights into predicting tumor recurrence post-radiotherapy. Additional contributions examine the significance of inflammatory biomarkers, the tumor microbiome, and potential molecular targets like Aspartate β-hydroxylase (ASPH) in enhancing therapeutic outcomes. This compilation serves as a valuable resource for researchers and clinicians aiming to advance personalized medicine approaches in HNSCC management.