This book delves into the pivotal role of Geographic Information Systems (GIS) and satellite imagery in safeguarding Syria's cultural heritage during conflict. It highlights Syria's rich historical significance and the impact of the civil war on its invaluable archaeological sites, including UNESCO World Heritage Sites. It explores how GIS technology aids in documenting damage, monitoring site conditions, and detecting looting, especially when direct access is restricted. Case studies, such as the site of Bosra, demonstrate the application of GIS tools like QGIS in assessing changes over time. The book also discusses challenges such as data accessibility and security concerns while emphasizing the importance of preserving cultural heritage for future generations. Ultimately, it serves as a compelling call to action for leveraging advanced technologies in heritage conservation amidst adversity.