Peripheral nerve injuries of the upper extremity are among the common clinical problems encountered in practice. These injuries present with both orthopedic and neurological findings, and their treatment requires a prolonged course marked by experience and patience-posing challenges for both the patient and the therapist. Due to the extended duration of nerve regeneration, there is a limited number of healthcare professionals with expertise in this area.This book does not aim to cover all aspects of the treatment of peripheral nerve injuries of the hand. Rather, its primary purpose is to provide fundamental knowledge to undergraduate and graduate students who seek to gain an understanding of this field. The initial chapters focus on the basic anatomical and biomechanical principles. Subsequent sections explore the cortical consequences of peripheral nerve injuries and discuss rehabilitation strategies through case-based examples.It is my sincere hope that this book will be a valuable resource for all its readers.